Siegfried Kasper Selected Research

5-HT1A Serotonin Receptor

1/2019	Epistasis of HTR1A and BDNF risk genes alters cortical 5-HT1A receptor binding: PET results link genotype to molecular phenotype in depression.
11/2014	Impact of COMT genotype on serotonin-1A receptor binding investigated with PET.
11/2012	Serotonin-1A receptor binding is positively associated with gray matter volume -- a multimodal neuroimaging study combining PET and structural MRI.
1/2011	Progesterone level predicts serotonin-1a receptor binding in the male human brain.
6/2010	Hypothalamic serotonin-1A receptor binding measured by PET predicts the plasma level of dehydroepiandrosterone sulfate in healthy women.
10/2009	The serotonin-1A receptor in anxiety disorders.
12/2008	The serotonin-1A receptor distribution in healthy men and women measured by PET and [carbonyl-11C]WAY-100635.
5/2007	Reduced serotonin-1A receptor binding in social anxiety disorder.
7/2002	Receptor and transporter imaging studies in schizophrenia, depression, bulimia and Tourette's disorder--implications for psychopharmacology.
6/2002	Brain serotonin 5-HT(1A) receptor binding in schizophrenia measured by positron emission tomography and [11C]WAY-100635.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Siegfried Kasper Research Topics

Disease

64	Major Depressive Disorder (Major Depressive Disorders) 11/2022 - 06/2004
37	Schizophrenia (Dementia Praecox) 05/2022 - 06/2002
32	Bipolar Disorder (Manic Depressive Psychosis) 05/2022 - 07/2002
32	Anxiety Disorders (Anxiety Disorder) 03/2022 - 10/2002
26	Mood Disorders (Mood Disorder) 11/2022 - 08/2002
25	Treatment-Resistant Depressive Disorder 10/2021 - 11/2004
19	Seasonal Affective Disorder 01/2020 - 04/2002
14	Psychotic Disorders (Schizoaffective Disorder) 05/2022 - 03/2003
14	Mental Disorders (Mental Disorder) 05/2022 - 07/2002
13	Depressive Disorder (Melancholia) 03/2022 - 03/2003
10	Social Phobia 12/2020 - 10/2002
10	Mania (Manias) 01/2017 - 08/2002
8	Panic Disorder (Panic Attack) 12/2020 - 10/2002
7	Drug-Related Side Effects and Adverse Reactions 12/2021 - 07/2012
7	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2021 - 02/2004
6	Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder) 01/2022 - 12/2014
6	Substance-Related Disorders (Drug Abuse) 01/2021 - 01/2008
6	Obsessive-Compulsive Disorder (Disorder, Obsessive-Compulsive) 12/2020 - 10/2002
6	Dementia (Dementias) 01/2017 - 01/2009
5	Hypertension (High Blood Pressure) 01/2022 - 10/2003
5	Psychomotor Agitation (Akathisia) 01/2019 - 05/2005
5	Feeding and Eating Disorders (Eating Disorder) 08/2015 - 06/2011
4	Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder) 11/2022 - 01/2008
4	Nausea 01/2021 - 03/2003
4	Headache (Headaches) 01/2021 - 01/2002
4	Sleepiness 01/2021 - 12/2012
4	Dizziness (Lightheadedness) 01/2021 - 12/2012
4	Weight Gain 01/2019 - 09/2011
3	Borderline Personality Disorder (Personality Disorders, Borderline) 11/2022 - 01/2003
3	Personality Disorders (Personality Disorder) 01/2021 - 07/2007
3	Agoraphobia 12/2020 - 01/2017
3	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2018 - 05/2005
3	Alzheimer Disease (Alzheimer's Disease) 03/2015 - 11/2002
3	Opioid-Related Disorders (Opiate Addiction) 02/2012 - 05/2005
2	Torsades de Pointes (Torsade de Pointes) 02/2022 - 12/2012
2	Genetic Risk Score 01/2022 - 01/2021
2	Hallucinations (Hallucination) 01/2021 - 11/2002
2	Fatigue 01/2021 - 03/2007
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2020 - 01/2020
2	Heart Diseases (Heart Disease) 06/2019 - 12/2012
2	Anhedonia 01/2019 - 08/2014
2	Neurobehavioral Manifestations 01/2019 - 09/2006
2	Phobic Disorders (Phobia) 01/2017 - 04/2015

Drug/Important Bio-Agent (IBA)

69	Antidepressive Agents (Antidepressants)IBA 11/2022 - 03/2003
37	Antipsychotic Agents (Antipsychotics)IBA 11/2022 - 06/2002
22	Escitalopram FDA Link 02/2022 - 01/2004
21	Selective Serotonin Reuptake Inhibitors (Serotonin Reuptake Inhibitors)IBA 06/2022 - 01/2002
20	Biological ProductsIBA 01/2022 - 06/2002
17	Pharmaceutical PreparationsIBA 12/2021 - 07/2002
13	Quetiapine Fumarate (Seroquel)FDA Link 11/2022 - 08/2002
12	lavender oilIBA 03/2022 - 09/2010
11	Pregabalin (Lyrica)FDA Link 01/2022 - 05/2006
10	Venlafaxine Hydrochloride (Effexor)FDA LinkGeneric 01/2020 - 01/2002
10	5-HT1A Serotonin ReceptorIBA 01/2019 - 06/2002
10	Serotonin (5 Hydroxytryptamine)IBA 07/2014 - 01/2002
9	EsketamineIBA 11/2022 - 11/2015
8	Ketamine FDA LinkGeneric 11/2022 - 04/2015
8	Citalopram FDA LinkGeneric 02/2022 - 06/2004
7	BenzodiazepinesIBA 12/2020 - 10/2002
7	LithiumIBA 12/2018 - 03/2003
7	agomelatine (S20098)IBA 04/2016 - 03/2007
6	Anti-Anxiety Agents (Anxiolytics)IBA 03/2022 - 03/2009
6	Psychotropic Drugs (Psychoactive Drugs)IBA 01/2022 - 07/2002
6	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 01/2011
6	Olanzapine (Zyprexa)FDA Link 01/2019 - 01/2007
6	Serotonin Plasma Membrane Transport Proteins (Serotonin Transporter)IBA 01/2017 - 07/2002
6	Norepinephrine (Noradrenaline)FDA LinkGeneric 06/2012 - 01/2002
5	Neurotransmitter Agents (Neurotransmitter)IBA 01/2019 - 05/2009
5	Biomarkers (Surrogate Marker)IBA 01/2019 - 09/2013
4	Therapeutic UsesIBA 01/2022 - 05/2009
4	Nasal SpraysIBA 01/2021 - 01/2020
4	Monoamine Oxidase (MAO)IBA 09/2020 - 11/2015
4	Dopamine (Intropin)FDA LinkGeneric 01/2020 - 01/2012
4	Carbamazepine (Tegretol)FDA LinkGeneric 01/2019 - 12/2004
3	Aripiprazole (Abilify)FDA Link 11/2022 - 12/2003
3	Clomipramine (Anafranil)FDA LinkGeneric 12/2021 - 10/2002
3	Lamotrigine (Lamictal)FDA LinkGeneric 01/2019 - 03/2004
3	ziprasidone (Geodon)FDA Link 01/2019 - 04/2007
3	Tricyclic Antidepressive Agents (Tricyclic Antidepressants)IBA 01/2018 - 01/2002
3	Ginkgo biloba extract (Rokan)IBA 06/2015 - 01/2009
3	Anticonvulsants (Antiepileptic Drugs)IBA 06/2015 - 09/2011
3	Carrier Proteins (Binding Protein)IBA 05/2015 - 02/2004
3	Risperidone (Risperdal Consta)FDA LinkGeneric 01/2015 - 01/2005
3	Paroxetine (Paxil)FDA LinkGeneric 06/2014 - 04/2009
3	Lorazepam (Ativan)FDA LinkGeneric 01/2014 - 01/2005
3	Serotonin and Noradrenaline Reuptake InhibitorsIBA 01/2013 - 03/2003
3	Milnacipran (Ixel)FDA Link 01/2011 - 03/2003
2	cariprazineIBA 05/2022 - 01/2019
2	CurcuminIBA 01/2022 - 10/2021
2	ZincIBA 01/2022 - 09/2011
2	3,4-methylenedioxyethamphetamine (MDEA)IBA 01/2021 - 01/2019
2	Dopamine Plasma Membrane Transport Proteins (Dopamine Transporter)IBA 01/2021 - 07/2002
2	Trazodone (Trittico)FDA LinkGeneric 01/2020 - 12/2012
2	mesoglycanIBA 01/2020 - 01/2017
2	Amphetamine (Amfetamine)FDA LinkGeneric 01/2020 - 01/2017
2	Chlormethiazole (Clomethiazole)IBA 01/2019 - 05/2005

Therapy/Procedure

22	Therapeutics 11/2022 - 08/2002
11	Phototherapy (Light Therapy) 01/2021 - 11/2002
11	Drug Therapy (Chemotherapy) 12/2018 - 01/2003
2	Aftercare (After-Treatment) 01/2019 - 11/2002